Chemical Constituents of Caesalpinia decapetala (Roth) Alston

The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston and investigates the bioactivities of the isolated compounds. Fourteen known compounds were isolated using column chromatography, and structural identification was performed by physical and spectral analyses....

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Autores principales: Wei, Xiao-Hua, Yang, Sheng-Jie, Liang, Na, Hu, De-Yu, Jin, Lin-Hong, Xue, Wei, Yang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270340/
https://www.ncbi.nlm.nih.gov/pubmed/23340256
http://dx.doi.org/10.3390/molecules18011325
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author Wei, Xiao-Hua
Yang, Sheng-Jie
Liang, Na
Hu, De-Yu
Jin, Lin-Hong
Xue, Wei
Yang, Song
author_facet Wei, Xiao-Hua
Yang, Sheng-Jie
Liang, Na
Hu, De-Yu
Jin, Lin-Hong
Xue, Wei
Yang, Song
author_sort Wei, Xiao-Hua
collection PubMed
description The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston and investigates the bioactivities of the isolated compounds. Fourteen known compounds were isolated using column chromatography, and structural identification was performed by physical and spectral analyses. The biological activities of the compounds were also evaluated by 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and 2,2-diphenlyl-1-picrylhydrazyl (DPPH) assays. Emodin (6), baicalein (9), and apigenin (12) displayed antitumor activities against the MGC-803 cell line, while quercetin (2), rutin (5), baicalein (9), and epicatechin (13) showed stronger DPPH scavenging activities compared with ascorbic acid. Andrographolide (1), quercetin (2), bergenin (4), rutin (5), emodin (6), betulin (7), baicalein (9), polydatin (10), salicin (11), and apigenin (12), were obtained from C. decapetala (Roth) Alston for the first time.
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spelling pubmed-62703402018-12-14 Chemical Constituents of Caesalpinia decapetala (Roth) Alston Wei, Xiao-Hua Yang, Sheng-Jie Liang, Na Hu, De-Yu Jin, Lin-Hong Xue, Wei Yang, Song Molecules Article The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston and investigates the bioactivities of the isolated compounds. Fourteen known compounds were isolated using column chromatography, and structural identification was performed by physical and spectral analyses. The biological activities of the compounds were also evaluated by 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and 2,2-diphenlyl-1-picrylhydrazyl (DPPH) assays. Emodin (6), baicalein (9), and apigenin (12) displayed antitumor activities against the MGC-803 cell line, while quercetin (2), rutin (5), baicalein (9), and epicatechin (13) showed stronger DPPH scavenging activities compared with ascorbic acid. Andrographolide (1), quercetin (2), bergenin (4), rutin (5), emodin (6), betulin (7), baicalein (9), polydatin (10), salicin (11), and apigenin (12), were obtained from C. decapetala (Roth) Alston for the first time. MDPI 2013-01-22 /pmc/articles/PMC6270340/ /pubmed/23340256 http://dx.doi.org/10.3390/molecules18011325 Text en © 2013 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wei, Xiao-Hua
Yang, Sheng-Jie
Liang, Na
Hu, De-Yu
Jin, Lin-Hong
Xue, Wei
Yang, Song
Chemical Constituents of Caesalpinia decapetala (Roth) Alston
title Chemical Constituents of Caesalpinia decapetala (Roth) Alston
title_full Chemical Constituents of Caesalpinia decapetala (Roth) Alston
title_fullStr Chemical Constituents of Caesalpinia decapetala (Roth) Alston
title_full_unstemmed Chemical Constituents of Caesalpinia decapetala (Roth) Alston
title_short Chemical Constituents of Caesalpinia decapetala (Roth) Alston
title_sort chemical constituents of caesalpinia decapetala (roth) alston
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270340/
https://www.ncbi.nlm.nih.gov/pubmed/23340256
http://dx.doi.org/10.3390/molecules18011325
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