Two New Chiratane-Type Triterpenoids from Swertia kouitchensis

Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1–4 showed moderat...

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Detalles Bibliográficos
Autores principales: Wan, Luo-Sheng, Liu, Ting-Ting, Lin, Xiao-Jun, Min, Qiu-Xia, Chen, Jia-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270363/
https://www.ncbi.nlm.nih.gov/pubmed/23873389
http://dx.doi.org/10.3390/molecules18078518
Descripción
Sumario:Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1–4 showed moderate inhibitory activity against the α-glucosidase (with IC(50) values ranging from 1,812 to 2,027 μM).

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