Two New Chiratane-Type Triterpenoids from Swertia kouitchensis

Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1–4 showed moderat...

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Autores principales: Wan, Luo-Sheng, Liu, Ting-Ting, Lin, Xiao-Jun, Min, Qiu-Xia, Chen, Jia-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270363/
https://www.ncbi.nlm.nih.gov/pubmed/23873389
http://dx.doi.org/10.3390/molecules18078518
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author Wan, Luo-Sheng
Liu, Ting-Ting
Lin, Xiao-Jun
Min, Qiu-Xia
Chen, Jia-Chun
author_facet Wan, Luo-Sheng
Liu, Ting-Ting
Lin, Xiao-Jun
Min, Qiu-Xia
Chen, Jia-Chun
author_sort Wan, Luo-Sheng
collection PubMed
description Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1–4 showed moderate inhibitory activity against the α-glucosidase (with IC(50) values ranging from 1,812 to 2,027 μM).
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spelling pubmed-62703632018-12-17 Two New Chiratane-Type Triterpenoids from Swertia kouitchensis Wan, Luo-Sheng Liu, Ting-Ting Lin, Xiao-Jun Min, Qiu-Xia Chen, Jia-Chun Molecules Article Two rare new chiratane-type triterpenoids, kouitchenoids A and B (1, 2), together with oleanolic acid (3) and ursolic acid (4), were isolated from ethanol extract of Swertia kouitchensis. The new structures were determined by the analysis of MS and NMR data. In addition, compounds 1–4 showed moderate inhibitory activity against the α-glucosidase (with IC(50) values ranging from 1,812 to 2,027 μM). MDPI 2013-07-18 /pmc/articles/PMC6270363/ /pubmed/23873389 http://dx.doi.org/10.3390/molecules18078518 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wan, Luo-Sheng
Liu, Ting-Ting
Lin, Xiao-Jun
Min, Qiu-Xia
Chen, Jia-Chun
Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
title Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
title_full Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
title_fullStr Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
title_full_unstemmed Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
title_short Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
title_sort two new chiratane-type triterpenoids from swertia kouitchensis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270363/
https://www.ncbi.nlm.nih.gov/pubmed/23873389
http://dx.doi.org/10.3390/molecules18078518
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