Targeting C-myc G-Quadruplex: Dual Recognition by Aminosugar-Bisbenzimidazoles with Varying Linker Lengths

G-quadruplexes are therapeutically important biological targets. In this report, we present biophysical studies of neomycin-Hoechst 33258 conjugates binding to a G-quadruplex derived from the C-myc promoter sequence. Our studies indicate that conjugation of neomycin to a G-quadruplex binder, Hoechst...

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Detalles Bibliográficos
Autores principales: Ranjan, Nihar, Arya, Dev P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270413/
https://www.ncbi.nlm.nih.gov/pubmed/24252993
http://dx.doi.org/10.3390/molecules181114228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270413/
https://www.ncbi.nlm.nih.gov/pubmed/24252993
http://dx.doi.org/10.3390/molecules181114228

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