A Soft Coral Natural Product, 11-Episinulariolide Acetate, Inhibits Gene Expression of Cyclooxygenase-2 and Interleukin-8 through Attenuation of Calcium Signaling

Epidermal growth factor receptor (EGFR) is overexpressed in many types of cancer cells. EGFR-mediated signaling involves inflammatory gene expression including cyclooxygenase (COX)-2 and interleukin (IL)-8, and is associated with cancer pathogenesis. In a search of phytochemicals with anti-inflammat...

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Detalles Bibliográficos
Autores principales: Hsu, Wen-Li, Chiu, Siou-Jin, Tsai, Yao-Ting, Chang, Che-Mai, Wang, Jaw-Yan, Wang, Eric Terry, Hou, Ming-Feng, Huang, Chiung-Yao, Sheu, Jyh-Horng, Chang, Wei-Chiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270419/
https://www.ncbi.nlm.nih.gov/pubmed/23774942
http://dx.doi.org/10.3390/molecules18067023

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