Oligonucleotide Tagging for Copper-Free Click Conjugation

Copper-free click chemistry between cyclooctynes and azide is a mild, fast and selective technology for conjugation of oligonucleotides. However, technology for site-specific introduction of the requisite probes by automated protocols is scarce, while the reported cyclooctynes are large and hydropho...

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Detalles Bibliográficos
Autores principales: Jawalekar, Anup M., Malik, Sudip, Verkade, Jorge M. M., Gibson, Brian, Barta, Nancy S., Hodges, John C., Rowan, Alan, van Delft, Floris L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270431/
https://www.ncbi.nlm.nih.gov/pubmed/23884112
http://dx.doi.org/10.3390/molecules18077346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270431/
https://www.ncbi.nlm.nih.gov/pubmed/23884112
http://dx.doi.org/10.3390/molecules18077346

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