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Synthesis and Radiolabelling of DOTA-Linked Glutamine Analogues with (67,68)Ga as Markers for Increased Glutamine Metabolism in Tumour Cells

DOTA-linked glutamine analogues with a C(6)- alkyl and polyethyleneglycol (PEG) chain between the chelating group and the l-glutamine moiety were synthesised and labelled with (67,68)Ga using established methods. High yields were achieved for the radiolabelling of the molecules with both radionuclid...

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Detalles Bibliográficos
Autores principales: Pellegrini, Paul A., Howell, Nicholas R., Shepherd, Rachael K., Lengkeek, Nigel A., Oehlke, Elisabeth, Katsifis, Andrew G., Greguric, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270456/
https://www.ncbi.nlm.nih.gov/pubmed/23783455
http://dx.doi.org/10.3390/molecules18067160

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