Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea

Fractionation of the chloroform extract of Wikstroemia coriacea led to the isolation of two new compounds, oleodaphnoic acid (1), a guaiane-type sesquiterpenoid, and coriaceol (2), an 1,5-diphenyl-1-pentanone analogue, together with nine known compounds. The structures of 1 and 2 were elucidated by...

Descripción completa

Detalles Bibliográficos
Autores principales: Ingert, Nicolas, Bombarda, Isabelle, Herbette, Gaëtan, Faure, Robert, Moretti, Christian, Raharivelomanana, Phila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270482/
https://www.ncbi.nlm.nih.gov/pubmed/23462531
http://dx.doi.org/10.3390/molecules18032988
_version_ 1783376709225021440
author Ingert, Nicolas
Bombarda, Isabelle
Herbette, Gaëtan
Faure, Robert
Moretti, Christian
Raharivelomanana, Phila
author_facet Ingert, Nicolas
Bombarda, Isabelle
Herbette, Gaëtan
Faure, Robert
Moretti, Christian
Raharivelomanana, Phila
author_sort Ingert, Nicolas
collection PubMed
description Fractionation of the chloroform extract of Wikstroemia coriacea led to the isolation of two new compounds, oleodaphnoic acid (1), a guaiane-type sesquiterpenoid, and coriaceol (2), an 1,5-diphenyl-1-pentanone analogue, together with nine known compounds. The structures of 1 and 2 were elucidated by extensive spectroscopic data analysis. The known compounds were oleodaphnal (3), indicanone (4), (5R,8R,8aR)-3,8-dimethyl-4,5,6,7,8,8a-hexahydro-5-(1-methylethenyl)-2(1H)-azulenone, (5), 1,5 diphenyl-1-pentanone (6), (+)-3-hydroxy-1,5-diphenyl-1-pentanone (7), umbelliferone (8), daphnoretin (9), β-sitostenone (10) and (−)-hinokinin (11).
format Online
Article
Text
id pubmed-6270482
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62704822018-12-20 Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea Ingert, Nicolas Bombarda, Isabelle Herbette, Gaëtan Faure, Robert Moretti, Christian Raharivelomanana, Phila Molecules Article Fractionation of the chloroform extract of Wikstroemia coriacea led to the isolation of two new compounds, oleodaphnoic acid (1), a guaiane-type sesquiterpenoid, and coriaceol (2), an 1,5-diphenyl-1-pentanone analogue, together with nine known compounds. The structures of 1 and 2 were elucidated by extensive spectroscopic data analysis. The known compounds were oleodaphnal (3), indicanone (4), (5R,8R,8aR)-3,8-dimethyl-4,5,6,7,8,8a-hexahydro-5-(1-methylethenyl)-2(1H)-azulenone, (5), 1,5 diphenyl-1-pentanone (6), (+)-3-hydroxy-1,5-diphenyl-1-pentanone (7), umbelliferone (8), daphnoretin (9), β-sitostenone (10) and (−)-hinokinin (11). MDPI 2013-03-05 /pmc/articles/PMC6270482/ /pubmed/23462531 http://dx.doi.org/10.3390/molecules18032988 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Ingert, Nicolas
Bombarda, Isabelle
Herbette, Gaëtan
Faure, Robert
Moretti, Christian
Raharivelomanana, Phila
Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea
title Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea
title_full Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea
title_fullStr Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea
title_full_unstemmed Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea
title_short Oleodaphnoic Acid and Coriaceol, Two New Natural Products from the Stem Bark of Wikstroemia coriacea
title_sort oleodaphnoic acid and coriaceol, two new natural products from the stem bark of wikstroemia coriacea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270482/
https://www.ncbi.nlm.nih.gov/pubmed/23462531
http://dx.doi.org/10.3390/molecules18032988
work_keys_str_mv AT ingertnicolas oleodaphnoicacidandcoriaceoltwonewnaturalproductsfromthestembarkofwikstroemiacoriacea
AT bombardaisabelle oleodaphnoicacidandcoriaceoltwonewnaturalproductsfromthestembarkofwikstroemiacoriacea
AT herbettegaetan oleodaphnoicacidandcoriaceoltwonewnaturalproductsfromthestembarkofwikstroemiacoriacea
AT faurerobert oleodaphnoicacidandcoriaceoltwonewnaturalproductsfromthestembarkofwikstroemiacoriacea
AT morettichristian oleodaphnoicacidandcoriaceoltwonewnaturalproductsfromthestembarkofwikstroemiacoriacea
AT raharivelomananaphila oleodaphnoicacidandcoriaceoltwonewnaturalproductsfromthestembarkofwikstroemiacoriacea

Ejemplares similares