Holographic Quantitative Structure-Activity Relationships of Tryptamine Derivatives at NMDA, 5HT(1A) and 5HT(2A) Receptors

Tryptamine derivatives (Ts) were found to inhibit the binding of [(3)H]MK-801, [(3)H]ketanserin and [(3)H]8-OH-DPAT to rat brain membranes. [(3)H]MK-801 labels the NMDA (N-methyl-D-aspartate) receptor, a ionotropic glutamate receptor which controls synaptic plasticity and memory function in the brai...

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Detalles Bibliográficos
Autores principales: Palangsuntikul, Rungtiva, Berner, Heinz, Berger, Michael L., Wolschann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270498/
https://www.ncbi.nlm.nih.gov/pubmed/23887721
http://dx.doi.org/10.3390/molecules18088799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270498/
https://www.ncbi.nlm.nih.gov/pubmed/23887721
http://dx.doi.org/10.3390/molecules18088799

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