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Holographic Quantitative Structure-Activity Relationships of Tryptamine Derivatives at NMDA, 5HT(1A) and 5HT(2A) Receptors
Tryptamine derivatives (Ts) were found to inhibit the binding of [(3)H]MK-801, [(3)H]ketanserin and [(3)H]8-OH-DPAT to rat brain membranes. [(3)H]MK-801 labels the NMDA (N-methyl-D-aspartate) receptor, a ionotropic glutamate receptor which controls synaptic plasticity and memory function in the brai...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270498/ https://www.ncbi.nlm.nih.gov/pubmed/23887721 http://dx.doi.org/10.3390/molecules18088799 |