Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity

Two new phenolic glycosides, named gnaphaffine A and B (compounds 1 and 2), were isolated from Gnaphalium affine. together with six known compounds, including caffeic acid (3), everlastoside L (4), isorhamnetin-7-O-β-d-glucopyranoside (5), quercetin-3-O-β-d-glucopyranoside (6), scutellarein-7-O-β-d-...

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Autores principales: Li, Junli, Huang, Doudou, Chen, Wansheng, Xi, Zhongxin, Chen, Cheng, Huang, Guanghui, Sun, Lianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270502/
https://www.ncbi.nlm.nih.gov/pubmed/23823875
http://dx.doi.org/10.3390/molecules18077751
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author Li, Junli
Huang, Doudou
Chen, Wansheng
Xi, Zhongxin
Chen, Cheng
Huang, Guanghui
Sun, Lianna
author_facet Li, Junli
Huang, Doudou
Chen, Wansheng
Xi, Zhongxin
Chen, Cheng
Huang, Guanghui
Sun, Lianna
author_sort Li, Junli
collection PubMed
description Two new phenolic glycosides, named gnaphaffine A and B (compounds 1 and 2), were isolated from Gnaphalium affine. together with six known compounds, including caffeic acid (3), everlastoside L (4), isorhamnetin-7-O-β-d-glucopyranoside (5), quercetin-3-O-β-d-glucopyranoside (6), scutellarein-7-O-β-d-glucoside (7) and api-genin-7-O-β-d-glucopyranoside (8). Their structures were elucidated by spectroscopic methods, including ESI-MS and 2D NMR spectroscopy (HMQC and HMBC). All compounds were evaluated for their anti-complementary activity on the classical pathway of the complement system in vitro.
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spelling pubmed-62705022018-12-17 Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity Li, Junli Huang, Doudou Chen, Wansheng Xi, Zhongxin Chen, Cheng Huang, Guanghui Sun, Lianna Molecules Article Two new phenolic glycosides, named gnaphaffine A and B (compounds 1 and 2), were isolated from Gnaphalium affine. together with six known compounds, including caffeic acid (3), everlastoside L (4), isorhamnetin-7-O-β-d-glucopyranoside (5), quercetin-3-O-β-d-glucopyranoside (6), scutellarein-7-O-β-d-glucoside (7) and api-genin-7-O-β-d-glucopyranoside (8). Their structures were elucidated by spectroscopic methods, including ESI-MS and 2D NMR spectroscopy (HMQC and HMBC). All compounds were evaluated for their anti-complementary activity on the classical pathway of the complement system in vitro. MDPI 2013-07-03 /pmc/articles/PMC6270502/ /pubmed/23823875 http://dx.doi.org/10.3390/molecules18077751 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Li, Junli
Huang, Doudou
Chen, Wansheng
Xi, Zhongxin
Chen, Cheng
Huang, Guanghui
Sun, Lianna
Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity
title Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity
title_full Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity
title_fullStr Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity
title_full_unstemmed Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity
title_short Two New Phenolic Glycosides from Gnaphalium affine D. Don and Their Anti-Complementary Activity
title_sort two new phenolic glycosides from gnaphalium affine d. don and their anti-complementary activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270502/
https://www.ncbi.nlm.nih.gov/pubmed/23823875
http://dx.doi.org/10.3390/molecules18077751
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