Synthesis and Antibacterial Evaluation of Some Novel Imidazole and Benzimidazole Sulfonamides

Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by (1)H-NMR, (13)C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacter...

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Detalles Bibliográficos
Autores principales: Al-Mohammed, Nassir N., Alias, Yatimah, Abdullah, Zanariah, Shakir, Raied M., Taha, Ekhlass M., Hamid, Aidil Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270528/
https://www.ncbi.nlm.nih.gov/pubmed/24077176
http://dx.doi.org/10.3390/molecules181011978
Descripción
Sumario:Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by (1)H-NMR, (13)C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria.

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