Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition

Pyrrolo[2,1-a]isoquinoline derivatives were synthesized by one-pot three-component reactions starting from isoquinoline, 2-bromoacetophenones and different non-symmetrical acetylenic dipolarophiles using 1,2-epoxypropane as solvent. The structure of the compounds was assigned by IR and NMR spectrosc...

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Detalles Bibliográficos
Autores principales: Dumitrascu, Florea, Georgescu, Emilian, Georgescu, Florentina, Popa, Marcel Mirel, Dumitrescu, Denisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270538/
https://www.ncbi.nlm.nih.gov/pubmed/23446920
http://dx.doi.org/10.3390/molecules18032635
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author Dumitrascu, Florea
Georgescu, Emilian
Georgescu, Florentina
Popa, Marcel Mirel
Dumitrescu, Denisa
author_facet Dumitrascu, Florea
Georgescu, Emilian
Georgescu, Florentina
Popa, Marcel Mirel
Dumitrescu, Denisa
author_sort Dumitrascu, Florea
collection PubMed
description Pyrrolo[2,1-a]isoquinoline derivatives were synthesized by one-pot three-component reactions starting from isoquinoline, 2-bromoacetophenones and different non-symmetrical acetylenic dipolarophiles using 1,2-epoxypropane as solvent. The structure of the compounds was assigned by IR and NMR spectroscopy.
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spelling pubmed-62705382018-12-20 Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition Dumitrascu, Florea Georgescu, Emilian Georgescu, Florentina Popa, Marcel Mirel Dumitrescu, Denisa Molecules Article Pyrrolo[2,1-a]isoquinoline derivatives were synthesized by one-pot three-component reactions starting from isoquinoline, 2-bromoacetophenones and different non-symmetrical acetylenic dipolarophiles using 1,2-epoxypropane as solvent. The structure of the compounds was assigned by IR and NMR spectroscopy. MDPI 2013-02-27 /pmc/articles/PMC6270538/ /pubmed/23446920 http://dx.doi.org/10.3390/molecules18032635 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Dumitrascu, Florea
Georgescu, Emilian
Georgescu, Florentina
Popa, Marcel Mirel
Dumitrescu, Denisa
Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
title Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
title_full Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
title_fullStr Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
title_full_unstemmed Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
title_short Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition
title_sort synthesis of pyrrolo[2,1-a]isoquinolines by multicomponent 1,3-dipolar cycloaddition
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270538/
https://www.ncbi.nlm.nih.gov/pubmed/23446920
http://dx.doi.org/10.3390/molecules18032635
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