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Synthesis of New Optically Active 2-Pyrrolidinones

A new class of optically active 2-pyrrolidinones was synthesized, starting from S-pyroglutamic acid, a well known natural chiral synthon. The synthetic design followed led to the insertion of various substituents at positions 1 and 5 of the 2-pyrrolidinone ring, including the imidazole moiety. Some...

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Detalles Bibliográficos
Autores principales:	Moutevelis-Minakakis, Panagiota, Papavassilopoulou, Eleni, Mavromoustakos, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270552/ https://www.ncbi.nlm.nih.gov/pubmed/23344188 http://dx.doi.org/10.3390/molecules18010050

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