‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach

An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO(3) catalyzed ‘one-pot’ cascade process involving formation of two new C–N bonds and one new C–O bond....

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Detalles Bibliográficos
Autores principales: Jiang, Baifeng, Zhou, Yu, Kong, Qingya, Jiang, Hualiang, Liu, Hong, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270568/
https://www.ncbi.nlm.nih.gov/pubmed/23344195
http://dx.doi.org/10.3390/molecules18010814
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author Jiang, Baifeng
Zhou, Yu
Kong, Qingya
Jiang, Hualiang
Liu, Hong
Li, Jian
author_facet Jiang, Baifeng
Zhou, Yu
Kong, Qingya
Jiang, Hualiang
Liu, Hong
Li, Jian
author_sort Jiang, Baifeng
collection PubMed
description An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO(3) catalyzed ‘one-pot’ cascade process involving formation of two new C–N bonds and one new C–O bond.
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spelling pubmed-62705682018-12-14 ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach Jiang, Baifeng Zhou, Yu Kong, Qingya Jiang, Hualiang Liu, Hong Li, Jian Molecules Article An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO(3) catalyzed ‘one-pot’ cascade process involving formation of two new C–N bonds and one new C–O bond. MDPI 2013-01-11 /pmc/articles/PMC6270568/ /pubmed/23344195 http://dx.doi.org/10.3390/molecules18010814 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Jiang, Baifeng
Zhou, Yu
Kong, Qingya
Jiang, Hualiang
Liu, Hong
Li, Jian
‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach
title ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach
title_full ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach
title_fullStr ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach
title_full_unstemmed ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach
title_short ‘One-pot’ Synthesis of Dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a Silver(I)-Catalyzed Cascade Approach
title_sort ‘one-pot’ synthesis of dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a silver(i)-catalyzed cascade approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270568/
https://www.ncbi.nlm.nih.gov/pubmed/23344195
http://dx.doi.org/10.3390/molecules18010814
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