TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines

We report herein an original and rapid synthesis of 2,3-diaryl N-tosylaziridines by TDAE strategy starting from ortho- or para-nitro(dichloromethyl)benzene derivatives and N-tosylimines. A mixture of cis/trans isomers was isolated from 1-(dichloromethyl)-4-nitrobenzene, whereas only trans-aziridines...

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Detalles Bibliográficos
Autores principales: Khoumeri, Omar, Spitz, Cédric, Terme, Thierry, Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270596/
https://www.ncbi.nlm.nih.gov/pubmed/23884113
http://dx.doi.org/10.3390/molecules18077364
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author Khoumeri, Omar
Spitz, Cédric
Terme, Thierry
Vanelle, Patrice
author_facet Khoumeri, Omar
Spitz, Cédric
Terme, Thierry
Vanelle, Patrice
author_sort Khoumeri, Omar
collection PubMed
description We report herein an original and rapid synthesis of 2,3-diaryl N-tosylaziridines by TDAE strategy starting from ortho- or para-nitro(dichloromethyl)benzene derivatives and N-tosylimines. A mixture of cis/trans isomers was isolated from 1-(dichloromethyl)-4-nitrobenzene, whereas only trans-aziridines were obtained from ortho-nitro derivatives.
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spelling pubmed-62705962018-12-17 TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines Khoumeri, Omar Spitz, Cédric Terme, Thierry Vanelle, Patrice Molecules Communication We report herein an original and rapid synthesis of 2,3-diaryl N-tosylaziridines by TDAE strategy starting from ortho- or para-nitro(dichloromethyl)benzene derivatives and N-tosylimines. A mixture of cis/trans isomers was isolated from 1-(dichloromethyl)-4-nitrobenzene, whereas only trans-aziridines were obtained from ortho-nitro derivatives. MDPI 2013-06-24 /pmc/articles/PMC6270596/ /pubmed/23884113 http://dx.doi.org/10.3390/molecules18077364 Text en © 2013 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Khoumeri, Omar
Spitz, Cédric
Terme, Thierry
Vanelle, Patrice
TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines
title TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines
title_full TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines
title_fullStr TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines
title_full_unstemmed TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines
title_short TDAE Strategy for the Synthesis of 2,3-Diaryl N-Tosylaziridines
title_sort tdae strategy for the synthesis of 2,3-diaryl n-tosylaziridines
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270596/
https://www.ncbi.nlm.nih.gov/pubmed/23884113
http://dx.doi.org/10.3390/molecules18077364
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