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Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway
Sinulariolide, an active compound isolated from the cultured soft coral Sinularia flexibilis, has potent anti-microbial and anti-tumorigenesis effects towards melanoma and bladder cancer cells. In this study, we investigated the effects of sinulariolide on hepatocellular carcinoma (HCC) cell growth...
Autores principales: | Chen, Yi-Jen, Su, Jui-Hsin, Tsao, Chia-Yu, Hung, Chun-Tzu, Chao, Hsiang-Hao, Lin, Jen-Jie, Liao, Ming-Hui, Yang, Zih-Yan, Huang, Han Hisang, Tsai, Feng-Jen, Weng, Shun-Hsiang, Wu, Yu-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270604/ https://www.ncbi.nlm.nih.gov/pubmed/23973991 http://dx.doi.org/10.3390/molecules180910146 |
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