Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect

Two cerebrosides named 1-O-β-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods inc...

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Detalles Bibliográficos
Autores principales: Wang, Ru-Feng, Wu, Xiu-Wen, Geng, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270611/
https://www.ncbi.nlm.nih.gov/pubmed/23344207
http://dx.doi.org/10.3390/molecules18011181
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author Wang, Ru-Feng
Wu, Xiu-Wen
Geng, Di
author_facet Wang, Ru-Feng
Wu, Xiu-Wen
Geng, Di
author_sort Wang, Ru-Feng
collection PubMed
description Two cerebrosides named 1-O-β-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide.
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spelling pubmed-62706112018-12-14 Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect Wang, Ru-Feng Wu, Xiu-Wen Geng, Di Molecules Article Two cerebrosides named 1-O-β-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time. Their structures were completely characterized by spectroscopic methods including IR, MS and NMR. Compound 1 exhibited moderate neuroprotective effect against SH-SY5Y cell damage induced by hydrogen peroxide. MDPI 2013-01-17 /pmc/articles/PMC6270611/ /pubmed/23344207 http://dx.doi.org/10.3390/molecules18011181 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Ru-Feng
Wu, Xiu-Wen
Geng, Di
Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_full Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_fullStr Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_full_unstemmed Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_short Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect
title_sort two cerebrosides isolated from the seeds of sterculia lychnophora and their neuroprotective effect
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270611/
https://www.ncbi.nlm.nih.gov/pubmed/23344207
http://dx.doi.org/10.3390/molecules18011181
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AT gengdi twocerebrosidesisolatedfromtheseedsofsterculialychnophoraandtheirneuroprotectiveeffect

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