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Schiff Bases: A Short Survey on an Evergreen Chemistry Tool

The review reports a short biography of the Italian naturalized chemist Hugo Schiff and an outline on the synthesis and use of his most popular discovery: the imines, very well known and popular as Schiff Bases. Recent developments on their “metallo-imines” variants have been described. The applicat...

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Detalles Bibliográficos
Autores principales: Qin, Wenling, Long, Sha, Panunzio, Mauro, Biondi, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270622/
https://www.ncbi.nlm.nih.gov/pubmed/24108395
http://dx.doi.org/10.3390/molecules181012264
Descripción
Sumario:The review reports a short biography of the Italian naturalized chemist Hugo Schiff and an outline on the synthesis and use of his most popular discovery: the imines, very well known and popular as Schiff Bases. Recent developments on their “metallo-imines” variants have been described. The applications of Schiff bases in organic synthesis as partner in Staudinger and hetero Diels-Alder reactions, as “privileged” ligands in the organometallic complexes and as biological active Schiff intermediates/targets have been reported as well.