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PM00104 (Zalypsis(®)): A Marine Derived Alkylating Agent
PM00104 (Zalypsis(®)) is a synthethic tetrahydroisoquinolone alkaloid, which is structurally similar to many marine organisms. The compound has been proposed as a potential chemotherapeutic agent in the treatment of solid human tumors and hematological malignancies. PM00104 is a DNA binding agent, c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270769/ https://www.ncbi.nlm.nih.gov/pubmed/25153860 http://dx.doi.org/10.3390/molecules190812328 |