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PM00104 (Zalypsis(®)): A Marine Derived Alkylating Agent

PM00104 (Zalypsis(®)) is a synthethic tetrahydroisoquinolone alkaloid, which is structurally similar to many marine organisms. The compound has been proposed as a potential chemotherapeutic agent in the treatment of solid human tumors and hematological malignancies. PM00104 is a DNA binding agent, c...

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Detalles Bibliográficos
Autores principales: Petek, Bradley J., Jones, Robin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270769/
https://www.ncbi.nlm.nih.gov/pubmed/25153860
http://dx.doi.org/10.3390/molecules190812328