Cargando…
Epigalloccatechin-3-gallate Inhibits Ocular Neovascularization and Vascular Permeability in Human Retinal Pigment Epithelial and Human Retinal Microvascular Endothelial Cells via Suppression of MMP-9 and VEGF Activation
Epigalloccatechin-3-gallate (EGCG) is the main polyphenol component of green tea (leaves of Camellia sinensis). EGCG is known for its antioxidant, anti-inflammatory, antiviral, and anti-carcinogenic properties. Here, we identify EGCG as a new inhibitor of ocular angiogenesis and its vascular permeab...
Autores principales: | Lee, Hak Sung, Jun, Jae-Hyun, Jung, Eun-Ha, Koo, Bon Am, Kim, Yeong Shik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270782/ https://www.ncbi.nlm.nih.gov/pubmed/25123184 http://dx.doi.org/10.3390/molecules190812150 |
Ejemplares similares
-
Preparation of arginine–glycine–aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization
por: Chang, Che-Yi, et al.
Publicado: (2016) -
Protective Effects of Epigallocatechin Gallate after UV Irradiation in Cultured Human Retinal Pigment Epithelial Cells
por: Yang, Seong-Won, et al.
Publicado: (2007) -
Inhibition of retinal neovascularization by siRNA targeting VEGF(165)
por: Xia, Xiao-bo, et al.
Publicado: (2008) -
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy
por: Arrigo, Alessandro, et al.
Publicado: (2022) -
Hyperactivation of retina by light in mice leads to photoreceptor cell death mediated by VEGF and retinal pigment epithelium permeability
por: Cachafeiro, M, et al.
Publicado: (2013)