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Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities
Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating their potential applications in medicine and a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270783/ https://www.ncbi.nlm.nih.gov/pubmed/24886942 http://dx.doi.org/10.3390/molecules19067169 |
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author | Lu, Shiqiong Tian, Jin Sun, Weibo Meng, Jiajia Wang, Xiaohan Fu, Xiaoxiang Wang, Ali Lai, Daowan Liu, Yang Zhou, Ligang |
author_facet | Lu, Shiqiong Tian, Jin Sun, Weibo Meng, Jiajia Wang, Xiaohan Fu, Xiaoxiang Wang, Ali Lai, Daowan Liu, Yang Zhou, Ligang |
author_sort | Lu, Shiqiong |
collection | PubMed |
description | Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating their potential applications in medicine and agriculture. At least 59 bis-naphtho-γ-pyrones from fungi have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, biosynthesis, and structure, as well as their biological activities. Some considerations regarding to synthesis, production, and medicinal and agricultural applications of bis-naphtho-γ-pyrones are also discussed. |
format | Online Article Text |
id | pubmed-6270783 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62707832018-12-21 Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities Lu, Shiqiong Tian, Jin Sun, Weibo Meng, Jiajia Wang, Xiaohan Fu, Xiaoxiang Wang, Ali Lai, Daowan Liu, Yang Zhou, Ligang Molecules Review Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating their potential applications in medicine and agriculture. At least 59 bis-naphtho-γ-pyrones from fungi have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, biosynthesis, and structure, as well as their biological activities. Some considerations regarding to synthesis, production, and medicinal and agricultural applications of bis-naphtho-γ-pyrones are also discussed. MDPI 2014-05-30 /pmc/articles/PMC6270783/ /pubmed/24886942 http://dx.doi.org/10.3390/molecules19067169 Text en © 2014 by the authors. licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Lu, Shiqiong Tian, Jin Sun, Weibo Meng, Jiajia Wang, Xiaohan Fu, Xiaoxiang Wang, Ali Lai, Daowan Liu, Yang Zhou, Ligang Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities |
title | Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities |
title_full | Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities |
title_fullStr | Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities |
title_full_unstemmed | Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities |
title_short | Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities |
title_sort | bis-naphtho-γ-pyrones from fungi and their bioactivities |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270783/ https://www.ncbi.nlm.nih.gov/pubmed/24886942 http://dx.doi.org/10.3390/molecules19067169 |
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