Cargando…

Pharmacokinetics, Tissue Distribution, Excretion and Plasma Protein Binding Studies of Wogonin in Rats

Wogonin is a natural anticancer candidate. The purpose of this study was to explore the pharmacokinetic profiles, tissue distribution, excretion and plasma protein binding of wogonin in Sprague—Dawley rats. A rapid, sensitive, and specific LC-MS/MS method has been developed for the determination of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Talbi, Amer, Zhao, Di, Liu, Qingwang, Li, Junxiu, Fan, Ali, Yang, Wei, Han, Xing, Chen, Xijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270787/ https://www.ncbi.nlm.nih.gov/pubmed/24786691 http://dx.doi.org/10.3390/molecules19055538

Ejemplares similares

Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat
por: Hung, Wei-Lun, et al.
Publicado: (2017)

Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Naringin in Aged Rats
por: Zeng, Xuan, et al.
Publicado: (2019)

Pharmacokinetics, Tissue Distribution and Excretion of Verticinone from F. hupehensis in Rats
por: Wu, Xiao, et al.
Publicado: (2014)

Pharmacokinetics, Tissue Distribution and Excretion of a Novel Diuretic (PU-48) in Rats
por: Zhang, Zhi-Yuan, et al.
Publicado: (2018)

Pharmacokinetics, tissue distribution, and excretion of zinc oxide nanoparticles
por: Baek, Miri, et al.
Publicado: (2012)

Pharmacokinetics, Tissue Distribution, and Excretion Characteristics of a Radix Polygoni Multiflori Extract in Rats
por: Cheng, Wenhao, et al.
Publicado: (2022)

Pharmacokinetics, Tissue Distribution, Metabolism and Excretion of a Novel COX-2 Inhibitor, Vitacoxib, in Rats
por: Wang, Jianzhong, et al.
Publicado: (2022)

Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats
por: Tan, Yin-Feng, et al.
Publicado: (2021)

Pharmacokinetics, absorption, distribution, metabolism and excretion of the MEK inhibitor zapnometinib in rats
por: Füll, Yvonne, et al.
Publicado: (2022)

Pharmacokinetics, Tissue Distribution and Excretion of Isoalantolactone and Alantolactone in Rats after Oral Administration of Radix Inulae Extract
por: Xu, Renjie, et al.
Publicado: (2015)

Mechanism in the existent difference in form of wogonin/wogonoside between plasma and intestine/liver in rats
por: Wang, Qian, et al.
Publicado: (2018)

Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011
por: Smith, Tara, et al.
Publicado: (2022)

The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats
por: Mu, Kunqian, et al.
Publicado: (2022)

Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical‐stage soluble guanylate cyclase stimulator in rats
por: Banijamali, Ali R., et al.
Publicado: (2020)

Pharmacokinetics, Tissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness
por: Hu, Xintong, et al.
Publicado: (2020)

Pharmacokinetics, bioavailability, metabolism and excretion of δ-viniferin in rats
por: Mao, Ping, et al.
Publicado: (2016)

Pharmacokinetics and Excretion of Berberine and Its Nine Metabolites in Rats
por: Feng, Xinchi, et al.
Publicado: (2021)

Tissue distribution and excretion kinetics of orally administered silica nanoparticles in rats
por: Lee, Jeong-A, et al.
Publicado: (2014)

Pharmacokinetics, tissue distribution, and plasma protein binding rate of curcumol in rats using liquid chromatography tandem mass spectrometry
por: Yang, Zhaoxu, et al.
Publicado: (2022)

Plasma Pharmacokinetics and Tissue Distribution of Doxorubicin in Rats following Treatment with Astragali Radix
por: Huang, Yin, et al.
Publicado: (2022)

Pharmacokinetic Data Show That Oxolinic Acid and Flumequine Are Absorbed and Excreted Rapidly From Plasma and Tissues of Lumpfish
por: Haugland, Gyri T., et al.
Publicado: (2019)

Comparative Pharmacokinetics of Baicalin, Wogonoside, Baicalein and Wogonin in Plasma after Oral Administration of Pure Baicalin, Radix Scutellariae and Scutellariae-Paeoniae Couple Extracts in Normal and Ulcerative Colitis Rats
por: Zhang, Zhen-Qiu, et al.
Publicado: (2013)

Current biological and pharmacological updates on wogonin
por: Rawat, Sarita, et al.
Publicado: (2020)

The Therapeutic Potential of Wogonin Observed in Preclinical Studies
por: Sharifi-Rad, Javad, et al.
Publicado: (2021)

Absorption, Distribution, Excretion, and Pharmacokinetics of (14)C-Pyronaridine Tetraphosphate in Male and Female Sprague-Dawley Rats
por: Park, Sang Hyun, et al.
Publicado: (2010)

The Pharmacokinetics of The Biliary Excretion of Ciprofloxacin
por: Ball, C. S., et al.
Publicado: (1989)

Pre-Clinical Pharmacokinetic Characterization, Tissue Distribution, and Excretion Studies of Novel Edaravone Oral Prodrug, TEJ-1704
por: Kang, Dong Wook, et al.
Publicado: (2021)

Determination of 6258-70, a new semi-synthetic taxane, in rat plasma and tissues: Application to the pharmacokinetics and tissue distribution study()
por: Zhao, Simin, et al.
Publicado: (2016)

Wogonin Attenuates Hippocampal Neuronal Loss and Cognitive Dysfunction in Trimethyltin-Intoxicated Rats
por: Lee, Bombi, et al.
Publicado: (2016)

Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice and Rats
por: Pang, Minyeong, et al.
Publicado: (2022)

Therapy Effects of Wogonin on Ovarian Cancer Cells
por: Ruibin, Jiang, et al.
Publicado: (2017)

Plasma Protein Binding Rate and Pharmacokinetics of Lekethromycin in Rats
por: Sun, Pan, et al.
Publicado: (2022)

Herb-drug interaction in the protective effect of Alpinia officinarum against gastric injury induced by indomethacin based on pharmacokinetic, tissue distribution and excretion studies in rats
por: Zhang, Xuguang, et al.
Publicado: (2021)

Differences in Multicomponent Pharmacokinetics, Tissue Distribution, and Excretion of Tripterygium Glycosides Tablets in Normal and Adriamycin–Induced Nephrotic Syndrome Rat Models and Correlations With Efficacy and Hepatotoxicity
por: Wu, Wei, et al.
Publicado: (2022)

Preclinical Drug Pharmacokinetic, Tissue Distribution and Excretion Profiles of the Novel Limonin Derivate HY-071085 as an Anti-Inflammatory and Analgesic Candidate in Rats and Beagle Dogs
por: Dong, Liping, et al.
Publicado: (2022)

Excretion and tissue distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
por: Piper, W N, et al.
Publicado: (1973)

Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies
por: Feng, Qianru, et al.
Publicado: (2017)

Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate
por: Yu, Lu, et al.
Publicado: (2020)

Pharmacokinetics, Tissue Distribution, Plasma Protein Binding Studies of 10-Dehydroxyl-12-Demethoxy-Conophylline, a Novel Anti-Tumor Candidate, in Rats
por: Jiang, Chengjun, et al.
Publicado: (2019)

Pharmacokinetics, Distribution, Metabolism, and Excretion of Omadacycline following a Single Intravenous or Oral Dose of (14)C-Omadacycline in Rats
por: Lin, Wen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_et89jqikhmudsggd458ve054oj