Cargando…

1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling

Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling. Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione, methoxy-naphthoquinones, and others) to cellular...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klotz, Lars-Oliver, Hou, Xiaoqing, Jacob, Claus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270801/ https://www.ncbi.nlm.nih.gov/pubmed/25232709 http://dx.doi.org/10.3390/molecules190914902

Ejemplares similares

Discovery and cellular stress pathway analysis of 1,4-naphthoquinone derivatives with novel, highly potent broad-spectrum anticancer activity
por: Ghosh, Sajal K., et al.
Publicado: (2018)

The Effects of 1,4-Naphthoquinone (NQ) and Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone, DHNQ) Individually and in Combination on Growth and Oxidative Stress in Maize (Zea mays L.) Seedlings
por: Karcz, Waldemar, et al.
Publicado: (2023)

5-Hydroxy-8-nitro-1,4-naphthoquinone
por: Tan, Daniel Teoh-Chuan, et al.
Publicado: (2008)

The Cellular and Molecular Determinants of Naphthoquinone-Dependent Activation of the Aryl Hydrocarbon Receptor
por: Faber, Samantha C., et al.
Publicado: (2020)

2-Chloro-3-(4-chlorobenzamido)-1,4-naphthoquinone
por: Brandy, Yakini, et al.
Publicado: (2008)

Removal of 1,4-Naphthoquinone by Birnessite-Catalyzed Oxidation: Effect of Phenolic Mediators and the Reaction Pathway
por: Lee, Han-Saem, et al.
Publicado: (2020)

Formation of 5-Hydroxy-3-methoxy-1,4-naphthoquinone and 8-Hydroxy-4-methoxy-1,2-naphthoquinone from Juglone
por: Blauenburg, Bastian, et al.
Publicado: (2012)

Aromatase inhibitory activity of 1,4-naphthoquinone derivatives and QSAR study
por: Prachayasittikul, Veda, et al.
Publicado: (2017)

1,4-Naphthoquinone Triggers Nematode Lethality by Inducing Oxidative Stress and Activating Insulin/IGF Signaling Pathway in Caenorhabditis elegans
por: Wang, Jia, et al.
Publicado: (2017)

t-BuOK mediated oxidative coupling amination of 1,4-naphthoquinone and related 3-indolylnaphthoquinones with amines
por: Dong, Yu, et al.
Publicado: (2021)

5-Chloro-8-hydroxy-6-methyl-1,4-naphthoquinone
por: Tan, Daniel Teoh-Chuan, et al.
Publicado: (2009)

Synthetic 1,4-Pyran Naphthoquinones Are Potent Inhibitors of Dengue Virus Replication
por: da Costa, Emmerson C. B., et al.
Publicado: (2013)

A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones
por: Reis, Marcelo Isidoro P, et al.
Publicado: (2015)

Synthesis and Antimicrobial Evaluation of 1,4‐Naphthoquinone Derivatives as Potential Antibacterial Agents
por: Ravichandiran, Palanisamy, et al.
Publicado: (2019)

1,4-Naphthoquinone Analogues: Potent Antibacterial Agents and Mode of Action Evaluation
por: Ravichandiran, Palanisamy, et al.
Publicado: (2019)

Evaluation of 1,4-naphthoquinone derivatives as antibacterial agents: activity and mechanistic studies
por: Liu, Zhizhuo, et al.
Publicado: (2022)

One-Pot Synthesis of Spiro-isobenzofuran Compounds via the Sequential Condensation/Oxidation Reaction of Ninhydrin with 4-Amino-1,2-naphthoquinones/2-Amino-1,4-naphthoquinones under Mild Conditions
por: Mousavi, Seyedeh Hekmat, et al.
Publicado: (2020)

Oxidative phenylamination of 5-substituted 1-hydroxynaphthalenes to N-phenyl-1,4-naphthoquinone monoimines by air and light “on water”
por: Benites, Julio, et al.
Publicado: (2014)

Sustainable Synthesis, Antiproliferative and Acetylcholinesterase Inhibition of 1,4- and 1,2-Naphthoquinone Derivatives
por: Cabral, Rafaela G., et al.
Publicado: (2023)

Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats
por: Palacios, Javier, et al.
Publicado: (2018)

Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone
por: Yu, Jin-Sheng, et al.
Publicado: (2012)

2,3-Dichloro-5,8-dimethoxy-1,4-naphthoquinone
por: Ukaegbu, Maraizu, et al.
Publicado: (2012)

Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
por: Dyshlovoy, Sergey A., et al.
Publicado: (2019)

Structural Changes Induced by Quinones: High‐Resolution Microwave Study of 1,4‐Naphthoquinone
por: Saxena, Shefali, et al.
Publicado: (2020)

Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2021)

The Relevance and Insights on 1,4-Naphthoquinones as Antimicrobial and Antitumoral Molecules: A Systematic Review
por: Navarro-Tovar, Gabriela, et al.
Publicado: (2023)

Discovery of New 2-Phenylamino-3-acyl-1,4-naphthoquinones as Inhibitors of Cancer Cells Proliferation: Searching for Intra-Cellular Targets Playing a Role in Cancer Cells Survival
por: Benites, Julio, et al.
Publicado: (2023)

DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate
por: Ourique, Fabiana, et al.
Publicado: (2015)

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta
por: Palacios, Javier, et al.
Publicado: (2016)

Editorial: Inter-cellular Electrical Signals in Plant Adaptation and Communication
por: Gilroy, Simon, et al.
Publicado: (2018)

2-Bromo-1,4-naphthoquinone: a potentially improved substitute of menadione in Apatone™ therapy
por: Graciani, F.S., et al.
Publicado: (2012)

Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plants
por: Widhalm, Joshua R, et al.
Publicado: (2016)

A Survey on the Reactivity of Phenyliodonium Ylide of 2-Hydroxy-1,4-Naphthoquinone with Amino Compounds
por: Spagou, Konstantina, et al.
Publicado: (2005)

Baker’s Yeast-Based Microbial Fuel Cell Mediated by 2-Methyl-1,4-Naphthoquinone
por: Rozene, Juste, et al.
Publicado: (2021)

Neuroprotective Effect of 1,4-Naphthoquinones in an In Vitro Model of Paraquat and 6-OHDA-Induced Neurotoxicity
por: Menchinskaya, Ekaterina, et al.
Publicado: (2021)

Convergent evolution of plant specialized 1,4-naphthoquinones: metabolism, trafficking, and resistance to their allelopathic effects
por: Meyer, George W, et al.
Publicado: (2020)

Hybrids of 1,4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study
por: Kadela-Tomanek, Monika, et al.
Publicado: (2023)

Genotoxicity of 1,4-benzoquinone and 1,4-naphthoquinone in relation to effects on glutathione and NAD(P)H levels in V79 cells.
por: Ludewig, G, et al.
Publicado: (1989)

Anti-Herpetic, Anti-Dengue and Antineoplastic Activities of Simple and Heterocycle-Fused Derivatives of Terpenyl-1,4-Naphthoquinone and 1,4-Anthraquinone †
por: Roa-Linares, Vicky C., et al.
Publicado: (2019)

Inter-Cellular Transport of Ran GTPase
por: Khuperkar, Deepak, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vd30aihp7lgb6785pqv702uqfn