Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production

A novel gedunin and two novel phragmalin-type limonoids, named carapanolides J–L (compounds 1–3) as well as a known gedunin-type limonoid 4 were isolated from the seeds of Carapa guianensis (andiroba). Their structures were determined on the basis of 1D and 2D NMR spectroscopy and HRFABMS. Compounds...

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Detalles Bibliográficos
Autores principales: Matsui, Yuuki, Kikuchi, Takashi, Inoue, Takanobu, Muraoka, Osamu, Yamada, Takeshi, Tanaka, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270836/
https://www.ncbi.nlm.nih.gov/pubmed/25347457
http://dx.doi.org/10.3390/molecules191117130
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author Matsui, Yuuki
Kikuchi, Takashi
Inoue, Takanobu
Muraoka, Osamu
Yamada, Takeshi
Tanaka, Reiko
author_facet Matsui, Yuuki
Kikuchi, Takashi
Inoue, Takanobu
Muraoka, Osamu
Yamada, Takeshi
Tanaka, Reiko
author_sort Matsui, Yuuki
collection PubMed
description A novel gedunin and two novel phragmalin-type limonoids, named carapanolides J–L (compounds 1–3) as well as a known gedunin-type limonoid 4 were isolated from the seeds of Carapa guianensis (andiroba). Their structures were determined on the basis of 1D and 2D NMR spectroscopy and HRFABMS. Compounds 1–4 were evaluated for their effects on the production of NO in LPS-activated mouse peritoneal macrophages.
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spelling pubmed-62708362019-01-07 Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production Matsui, Yuuki Kikuchi, Takashi Inoue, Takanobu Muraoka, Osamu Yamada, Takeshi Tanaka, Reiko Molecules Article A novel gedunin and two novel phragmalin-type limonoids, named carapanolides J–L (compounds 1–3) as well as a known gedunin-type limonoid 4 were isolated from the seeds of Carapa guianensis (andiroba). Their structures were determined on the basis of 1D and 2D NMR spectroscopy and HRFABMS. Compounds 1–4 were evaluated for their effects on the production of NO in LPS-activated mouse peritoneal macrophages. MDPI 2014-10-24 /pmc/articles/PMC6270836/ /pubmed/25347457 http://dx.doi.org/10.3390/molecules191117130 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Matsui, Yuuki
Kikuchi, Takashi
Inoue, Takanobu
Muraoka, Osamu
Yamada, Takeshi
Tanaka, Reiko
Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production
title Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production
title_full Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production
title_fullStr Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production
title_full_unstemmed Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production
title_short Carapanolides J–L from the Seeds of Carapa guianensis (Andiroba) and Their Effects on LPS-Activated NO Production
title_sort carapanolides j–l from the seeds of carapa guianensis (andiroba) and their effects on lps-activated no production
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270836/
https://www.ncbi.nlm.nih.gov/pubmed/25347457
http://dx.doi.org/10.3390/molecules191117130
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