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Synthesis of Extended Uridine Phosphonates Derived from an Allosteric P2Y(2) Receptor Ligand

In this study we report the synthesis of C5/C6-fused uridine phosphonates that are structurally related to earlier reported allosteric P2Y(2) receptor ligands. A silyl-Hilbert-Johnson reaction of six quinazoline-2,4-(1H,3H)-dione-like base moieties with a suitable ribofuranosephosphonate afforded th...

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Detalles Bibliográficos
Autores principales:	Song, Lijun, Risseeuw, Martijn D. P., Karalic, Izet, Barrett, Matthew O., Brown, Kyle A., Harden, T. Kendall, Van Calenbergh, Serge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270895/ https://www.ncbi.nlm.nih.gov/pubmed/24714193 http://dx.doi.org/10.3390/molecules19044313

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