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Applications of Copper-Catalyzed Click Chemistry in Activity-Based Protein Profiling
Activity-based protein profiling (ABPP) is a chemical proteomic technique that enables the interrogation of protein activity directly within complex proteomes. Given the dominant role of posttranslational modifications in regulating protein function in vivo, ABPP provides a direct readout of activit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270908/ https://www.ncbi.nlm.nih.gov/pubmed/24473203 http://dx.doi.org/10.3390/molecules19021378 |