miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives

The goal of the present paper is to establish and validate the link between cancer diagnosis and therapy by microRNAs detection. The induction in vitro of some specific microRNAs after treatment with MDR ligands has been outlined. Starting from the results obtained by in vitro induction of MDCK and...

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Autores principales: Gisel, Andreas, Valvano, Mirna, Ghafir El Idrissi, Imane, Nardulli, Patrizia, Azzariti, Amalia, Carrieri, Antonio, Contino, Marialessandra, Colabufo, Nicola Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270919/
https://www.ncbi.nlm.nih.gov/pubmed/24786846
http://dx.doi.org/10.3390/molecules19055611
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author Gisel, Andreas
Valvano, Mirna
Ghafir El Idrissi, Imane
Nardulli, Patrizia
Azzariti, Amalia
Carrieri, Antonio
Contino, Marialessandra
Colabufo, Nicola Antonio
author_facet Gisel, Andreas
Valvano, Mirna
Ghafir El Idrissi, Imane
Nardulli, Patrizia
Azzariti, Amalia
Carrieri, Antonio
Contino, Marialessandra
Colabufo, Nicola Antonio
author_sort Gisel, Andreas
collection PubMed
description The goal of the present paper is to establish and validate the link between cancer diagnosis and therapy by microRNAs detection. The induction in vitro of some specific microRNAs after treatment with MDR ligands has been outlined. Starting from the results obtained by in vitro induction of MDCK and MDCK-MDR1 cells treated by a MDR1 ligand, a new scenario in the early diagnosis and chemotherapy could be disclosed. To corroborate this perspective a short overview on pancreatic cancer diagnosis and chemotherapeutic treatment has been reported.
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spelling pubmed-62709192018-12-21 miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives Gisel, Andreas Valvano, Mirna Ghafir El Idrissi, Imane Nardulli, Patrizia Azzariti, Amalia Carrieri, Antonio Contino, Marialessandra Colabufo, Nicola Antonio Molecules Article The goal of the present paper is to establish and validate the link between cancer diagnosis and therapy by microRNAs detection. The induction in vitro of some specific microRNAs after treatment with MDR ligands has been outlined. Starting from the results obtained by in vitro induction of MDCK and MDCK-MDR1 cells treated by a MDR1 ligand, a new scenario in the early diagnosis and chemotherapy could be disclosed. To corroborate this perspective a short overview on pancreatic cancer diagnosis and chemotherapeutic treatment has been reported. MDPI 2014-04-30 /pmc/articles/PMC6270919/ /pubmed/24786846 http://dx.doi.org/10.3390/molecules19055611 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Gisel, Andreas
Valvano, Mirna
Ghafir El Idrissi, Imane
Nardulli, Patrizia
Azzariti, Amalia
Carrieri, Antonio
Contino, Marialessandra
Colabufo, Nicola Antonio
miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
title miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
title_full miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
title_fullStr miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
title_full_unstemmed miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
title_short miRNAs for the Detection of MultiDrug Resistance: Overview and Perspectives
title_sort mirnas for the detection of multidrug resistance: overview and perspectives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270919/
https://www.ncbi.nlm.nih.gov/pubmed/24786846
http://dx.doi.org/10.3390/molecules19055611
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