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Curcumin Protects against CCl(4)-Induced Liver Fibrosis in Rats by Inhibiting HIF-1α Through an ERK-Dependent Pathway

The ERK/HIF-1α signaling pathway is believed to play an important role in the genesis of progressive fibrosis. An increasing expression of HIF-1α and ERK accompanies CCl(4)-induced liver fibrosis in rats. Curcumin is verified to have antifibrotic effects in several kinds of liver fibrosis models. Th...

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Detalles Bibliográficos
Autores principales:	Zhao, Yanling, Ma, Xiao, Wang, Jiabo, He, Xuan, Hu, Yan, Zhang, Ping, Wang, Ruilin, Li, Ruisheng, Gong, Man, Luo, Shengqiang, Xiao, Xiaohe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270950/ https://www.ncbi.nlm.nih.gov/pubmed/25407718 http://dx.doi.org/10.3390/molecules191118767

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