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Inhibitory Effect of Corn Silk on Skin Pigmentation
In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein expression. The corn silk extract applied on Melan-A ce...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270964/ https://www.ncbi.nlm.nih.gov/pubmed/24595276 http://dx.doi.org/10.3390/molecules19032808 |
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author | Choi, Sang Yoon Lee, Yeonmi Kim, Sung Soo Ju, Hyun Min Baek, Ji Hwoon Park, Chul-Soo Lee, Dong-Hyuk |
author_facet | Choi, Sang Yoon Lee, Yeonmi Kim, Sung Soo Ju, Hyun Min Baek, Ji Hwoon Park, Chul-Soo Lee, Dong-Hyuk |
author_sort | Choi, Sang Yoon |
collection | PubMed |
description | In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein expression. The corn silk extract applied on Melan-A cells at a concentration of 100 ppm decreased melanin production by 37.2% without cytotoxicity. This was a better result than arbutin, a positive whitening agent, which exhibited a 26.8% melanin production inhibitory effect at the same concentration. The corn silk extract did not suppress tyrosinase activity but greatly reduced the expression of tyrosinase in Melan-A cells. In addition, corn silk extract was applied to the human face with hyperpigmentation, and skin color was measured to examine the degree of skin pigment reduction. The application of corn silk extract on faces with hyperpigmentation significantly reduced skin pigmentation without abnormal reactions. Based on the results above, corn silk has good prospects for use as a material for suppressing skin pigmentation. |
format | Online Article Text |
id | pubmed-6270964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62709642018-12-20 Inhibitory Effect of Corn Silk on Skin Pigmentation Choi, Sang Yoon Lee, Yeonmi Kim, Sung Soo Ju, Hyun Min Baek, Ji Hwoon Park, Chul-Soo Lee, Dong-Hyuk Molecules Article In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein expression. The corn silk extract applied on Melan-A cells at a concentration of 100 ppm decreased melanin production by 37.2% without cytotoxicity. This was a better result than arbutin, a positive whitening agent, which exhibited a 26.8% melanin production inhibitory effect at the same concentration. The corn silk extract did not suppress tyrosinase activity but greatly reduced the expression of tyrosinase in Melan-A cells. In addition, corn silk extract was applied to the human face with hyperpigmentation, and skin color was measured to examine the degree of skin pigment reduction. The application of corn silk extract on faces with hyperpigmentation significantly reduced skin pigmentation without abnormal reactions. Based on the results above, corn silk has good prospects for use as a material for suppressing skin pigmentation. MDPI 2014-03-03 /pmc/articles/PMC6270964/ /pubmed/24595276 http://dx.doi.org/10.3390/molecules19032808 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Choi, Sang Yoon Lee, Yeonmi Kim, Sung Soo Ju, Hyun Min Baek, Ji Hwoon Park, Chul-Soo Lee, Dong-Hyuk Inhibitory Effect of Corn Silk on Skin Pigmentation |
title | Inhibitory Effect of Corn Silk on Skin Pigmentation |
title_full | Inhibitory Effect of Corn Silk on Skin Pigmentation |
title_fullStr | Inhibitory Effect of Corn Silk on Skin Pigmentation |
title_full_unstemmed | Inhibitory Effect of Corn Silk on Skin Pigmentation |
title_short | Inhibitory Effect of Corn Silk on Skin Pigmentation |
title_sort | inhibitory effect of corn silk on skin pigmentation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270964/ https://www.ncbi.nlm.nih.gov/pubmed/24595276 http://dx.doi.org/10.3390/molecules19032808 |
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