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Polylactide Conjugates of Camptothecin with Different Drug Release Abilities

Camptothecin-polylactide conjugates (CMPT-PLA) were synthesized by covalent incorporation of CMPT into PLA of different microstructure, i.e., atactic PLA and atactic-block-isotactically enriched PLA (P(m) = 0.79) via urethane bonds. The kinetic release of CPMT from CMPT-PLA conjugates, tested in vit...

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Detalles Bibliográficos
Autores principales:	Oledzka, Ewa, Horeglad, Paweł, Gruszczyńska, Zuzanna, Plichta, Andrzej, Nałęcz-Jawecki, Grzegorz, Sobczak, Marcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270997/ https://www.ncbi.nlm.nih.gov/pubmed/25429566 http://dx.doi.org/10.3390/molecules191219460

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