Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives

Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted the attention of many researchers to explore th...

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Detalles Bibliográficos
Autores principales: Zhang, Pengxuan, Tang, Yuping, Li, Nian-Guang, Zhu, Yue, Duan, Jin-Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271019/
https://www.ncbi.nlm.nih.gov/pubmed/25314606
http://dx.doi.org/10.3390/molecules191016458
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author Zhang, Pengxuan
Tang, Yuping
Li, Nian-Guang
Zhu, Yue
Duan, Jin-Ao
author_facet Zhang, Pengxuan
Tang, Yuping
Li, Nian-Guang
Zhu, Yue
Duan, Jin-Ao
author_sort Zhang, Pengxuan
collection PubMed
description Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted the attention of many researchers to explore the compound with potent biological activities. This review aims to summarize its bioactivities, synthetic methods and derivatives, which will be helpful for further study and development of CAPE and its derivatives.
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spelling pubmed-62710192018-12-27 Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives Zhang, Pengxuan Tang, Yuping Li, Nian-Guang Zhu, Yue Duan, Jin-Ao Molecules Review Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted the attention of many researchers to explore the compound with potent biological activities. This review aims to summarize its bioactivities, synthetic methods and derivatives, which will be helpful for further study and development of CAPE and its derivatives. MDPI 2014-10-13 /pmc/articles/PMC6271019/ /pubmed/25314606 http://dx.doi.org/10.3390/molecules191016458 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Pengxuan
Tang, Yuping
Li, Nian-Guang
Zhu, Yue
Duan, Jin-Ao
Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
title Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
title_full Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
title_fullStr Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
title_full_unstemmed Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
title_short Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives
title_sort bioactivity and chemical synthesis of caffeic acid phenethyl ester and its derivatives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271019/
https://www.ncbi.nlm.nih.gov/pubmed/25314606
http://dx.doi.org/10.3390/molecules191016458
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