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Chemical Constituents and Bioactivities of Clinacanthus nutans Aerial Parts

Four new sulfur-containing compounds, named clinamides A-C (1–3), and 2-cis-entadamide A (4), were isolated together with three known compounds from the bioactive ethanol extract of the aerial parts of Clinacanthus nutans. These secondary metabolites possess sulfur atoms and acrylamide functionaliti...

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Detalles Bibliográficos
Autores principales: Tu, Shu-Fen, Liu, Rosa Huang, Cheng, Yuan-Bin, Hsu, Yu-Ming, Du, Ying-Chi, El-Shazly, Mohamed, Wu, Yang-Chang, Chang, Fang-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271080/
https://www.ncbi.nlm.nih.gov/pubmed/25490430
http://dx.doi.org/10.3390/molecules191220382
Descripción
Sumario:Four new sulfur-containing compounds, named clinamides A-C (1–3), and 2-cis-entadamide A (4), were isolated together with three known compounds from the bioactive ethanol extract of the aerial parts of Clinacanthus nutans. These secondary metabolites possess sulfur atoms and acrylamide functionalities. The structures of the isolated components were established by interpretation of their spectroscopic data, especially 1D and 2D NMR.