Anti-Inflammatory Effect of Methylpenicinoline from a Marine Isolate of Penicillium sp. (SF-5995): Inhibition of NF-κB and MAPK Pathways in Lipopolysaccharide-Induced RAW264.7 Macrophages and BV2 Microglia

In the course of a search for anti-inflammatory metabolites from marine-derived fungi, methylpenicinoline (1) was isolated from a marine isolate of Penicillin sp. Compound 1 inhibited lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production by suppressing the expression of inducible NO synth...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Cheol, Lee, Hee-Suk, Ko, Wonmin, Lee, Dong-Sung, Sohn, Jae Hak, Yim, Joung Han, Kim, Youn-Chul, Oh, Hyuncheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271136/
https://www.ncbi.nlm.nih.gov/pubmed/25379644
http://dx.doi.org/10.3390/molecules191118073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271136/
https://www.ncbi.nlm.nih.gov/pubmed/25379644
http://dx.doi.org/10.3390/molecules191118073

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