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Understanding the Interaction Determinants of CAPN1 Inhibition by CAST4 from Bovines Using Molecular Modeling Techniques

HCV-induced CAPN activation and its effects on virus-infected cells in a host-immune system have been studied recently. It has been shown that the HCV-nonstructural 5A protein acts as both an inducer and a substrate for host CAPN protease; it participates in suppressing the TNF-α-induced apoptosis r...

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Detalles Bibliográficos
Autores principales: Chai, Han-Ha, Lim, Dajeong, Jung, Eunkyoung, Choi, Bong-Hwan, Cho, Yong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271145/
https://www.ncbi.nlm.nih.gov/pubmed/25215589
http://dx.doi.org/10.3390/molecules190914316