Antiprotozoal Activity of Buxus sempervirens and Activity-Guided Isolation of O-tigloylcyclovirobuxeine-B as the Main Constituent Active against Plasmodium falciparum ‡

Buxus sempervirens L. (European Box, Buxaceae) has been used in ethnomedicine to treat malaria. In the course of our screening of plant extracts for antiprotozoal activity, a CH(2)Cl(2) extract from leaves of B. sempervirens showed selective in vitro activity against Plasmodium falciparum (IC(50) =...

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Detalles Bibliográficos
Autores principales: Althaus, Julia B., Jerz, Gerold, Winterhalter, Peter, Kaiser, Marcel, Brun, Reto, Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271158/
https://www.ncbi.nlm.nih.gov/pubmed/24838073
http://dx.doi.org/10.3390/molecules19056184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271158/
https://www.ncbi.nlm.nih.gov/pubmed/24838073
http://dx.doi.org/10.3390/molecules19056184

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