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Antiprotozoal Activity of Buxus sempervirens and Activity-Guided Isolation of O-tigloylcyclovirobuxeine-B as the Main Constituent Active against Plasmodium falciparum ‡
Buxus sempervirens L. (European Box, Buxaceae) has been used in ethnomedicine to treat malaria. In the course of our screening of plant extracts for antiprotozoal activity, a CH(2)Cl(2) extract from leaves of B. sempervirens showed selective in vitro activity against Plasmodium falciparum (IC(50) =...
Autores principales: | Althaus, Julia B., Jerz, Gerold, Winterhalter, Peter, Kaiser, Marcel, Brun, Reto, Schmidt, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271158/ https://www.ncbi.nlm.nih.gov/pubmed/24838073 http://dx.doi.org/10.3390/molecules19056184 |
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