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New Flavanol and Cycloartane Glucosides from Landoltia punctata

Chemical investigation on the constituents of Landoltia punctata led to the isolation and identification of 17 compounds, four of which were new and identified as (3β,24S)-9,19-cycloartane-3,22,24,25-tetraol 3-O-[β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→6)]-β-d-glucopyranoside (1), (3β,24S)-...

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Autores principales: Wang, Nini, Xu, Guobo, Fang, Yang, Yang, Tao, Zhao, Hai, Li, Guoyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271191/
https://www.ncbi.nlm.nih.gov/pubmed/24858096
http://dx.doi.org/10.3390/molecules19056623
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author Wang, Nini
Xu, Guobo
Fang, Yang
Yang, Tao
Zhao, Hai
Li, Guoyou
author_facet Wang, Nini
Xu, Guobo
Fang, Yang
Yang, Tao
Zhao, Hai
Li, Guoyou
author_sort Wang, Nini
collection PubMed
description Chemical investigation on the constituents of Landoltia punctata led to the isolation and identification of 17 compounds, four of which were new and identified as (3β,24S)-9,19-cycloartane-3,22,24,25-tetraol 3-O-[β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→6)]-β-d-glucopyranoside (1), (3β,24S)-9,19-cycloartane-3,24,25-triol 3-O-[β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→6)]-β-d-glucopyranoside (2), 3,4'-dihydroxy-7,3'-dimethoxyflavan-5-O-β-d-glucopyranoside (3) and 3,4'-dihydroxy-4,7,3'-trimethoxyflavan-5-O-β-d-glucopyranoside (4). Their structures were elucidated by spectroscopic, chemical, and biochemical methods. Thus, cycloartane triterpenoids were discovered in the Lemnaceae family for the first time. Compound 3 showed antioxidant capacity in the positively charged 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid radical (ABTS(+•)) and superoxide anion radical scavenging assays.
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spelling pubmed-62711912018-12-21 New Flavanol and Cycloartane Glucosides from Landoltia punctata Wang, Nini Xu, Guobo Fang, Yang Yang, Tao Zhao, Hai Li, Guoyou Molecules Article Chemical investigation on the constituents of Landoltia punctata led to the isolation and identification of 17 compounds, four of which were new and identified as (3β,24S)-9,19-cycloartane-3,22,24,25-tetraol 3-O-[β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→6)]-β-d-glucopyranoside (1), (3β,24S)-9,19-cycloartane-3,24,25-triol 3-O-[β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→6)]-β-d-glucopyranoside (2), 3,4'-dihydroxy-7,3'-dimethoxyflavan-5-O-β-d-glucopyranoside (3) and 3,4'-dihydroxy-4,7,3'-trimethoxyflavan-5-O-β-d-glucopyranoside (4). Their structures were elucidated by spectroscopic, chemical, and biochemical methods. Thus, cycloartane triterpenoids were discovered in the Lemnaceae family for the first time. Compound 3 showed antioxidant capacity in the positively charged 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid radical (ABTS(+•)) and superoxide anion radical scavenging assays. MDPI 2014-05-22 /pmc/articles/PMC6271191/ /pubmed/24858096 http://dx.doi.org/10.3390/molecules19056623 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Nini
Xu, Guobo
Fang, Yang
Yang, Tao
Zhao, Hai
Li, Guoyou
New Flavanol and Cycloartane Glucosides from Landoltia punctata
title New Flavanol and Cycloartane Glucosides from Landoltia punctata
title_full New Flavanol and Cycloartane Glucosides from Landoltia punctata
title_fullStr New Flavanol and Cycloartane Glucosides from Landoltia punctata
title_full_unstemmed New Flavanol and Cycloartane Glucosides from Landoltia punctata
title_short New Flavanol and Cycloartane Glucosides from Landoltia punctata
title_sort new flavanol and cycloartane glucosides from landoltia punctata
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271191/
https://www.ncbi.nlm.nih.gov/pubmed/24858096
http://dx.doi.org/10.3390/molecules19056623
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