Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety

Six novel chloro-containing 1-aryl-3-oxypyrazoles TMa–TMf with an oximino ester or an oximino amide moiety were prepared by the reaction of 1-aryl-1H-pyrazol-3-ols with benzyl bromide. Their structures were characterized by (1)H-NMR, (13)C-NMR, IR, MS, and elemental analysis. A preliminary in vitro...

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Detalles Bibliográficos
Autores principales: Liu, Yuanyuan, Li, Yi, Chen, Nanqing, Lv, Kunzhi, Zhou, Chao, Xiong, Xiaohui, Li, Fangshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271209/
https://www.ncbi.nlm.nih.gov/pubmed/24941339
http://dx.doi.org/10.3390/molecules19068140
Descripción
Sumario:Six novel chloro-containing 1-aryl-3-oxypyrazoles TMa–TMf with an oximino ester or an oximino amide moiety were prepared by the reaction of 1-aryl-1H-pyrazol-3-ols with benzyl bromide. Their structures were characterized by (1)H-NMR, (13)C-NMR, IR, MS, and elemental analysis. A preliminary in vitro bioassay indicated that compounds TMa, TMe and TMf displayed excellent fungicidal activity against Rhizoctonia solani and could be used as potential lead compounds for further development of novel fungicides.

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