Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety

Six novel chloro-containing 1-aryl-3-oxypyrazoles TMa–TMf with an oximino ester or an oximino amide moiety were prepared by the reaction of 1-aryl-1H-pyrazol-3-ols with benzyl bromide. Their structures were characterized by (1)H-NMR, (13)C-NMR, IR, MS, and elemental analysis. A preliminary in vitro...

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Detalles Bibliográficos
Autores principales: Liu, Yuanyuan, Li, Yi, Chen, Nanqing, Lv, Kunzhi, Zhou, Chao, Xiong, Xiaohui, Li, Fangshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271209/
https://www.ncbi.nlm.nih.gov/pubmed/24941339
http://dx.doi.org/10.3390/molecules19068140
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author Liu, Yuanyuan
Li, Yi
Chen, Nanqing
Lv, Kunzhi
Zhou, Chao
Xiong, Xiaohui
Li, Fangshi
author_facet Liu, Yuanyuan
Li, Yi
Chen, Nanqing
Lv, Kunzhi
Zhou, Chao
Xiong, Xiaohui
Li, Fangshi
author_sort Liu, Yuanyuan
collection PubMed
description Six novel chloro-containing 1-aryl-3-oxypyrazoles TMa–TMf with an oximino ester or an oximino amide moiety were prepared by the reaction of 1-aryl-1H-pyrazol-3-ols with benzyl bromide. Their structures were characterized by (1)H-NMR, (13)C-NMR, IR, MS, and elemental analysis. A preliminary in vitro bioassay indicated that compounds TMa, TMe and TMf displayed excellent fungicidal activity against Rhizoctonia solani and could be used as potential lead compounds for further development of novel fungicides.
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spelling pubmed-62712092018-12-21 Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety Liu, Yuanyuan Li, Yi Chen, Nanqing Lv, Kunzhi Zhou, Chao Xiong, Xiaohui Li, Fangshi Molecules Article Six novel chloro-containing 1-aryl-3-oxypyrazoles TMa–TMf with an oximino ester or an oximino amide moiety were prepared by the reaction of 1-aryl-1H-pyrazol-3-ols with benzyl bromide. Their structures were characterized by (1)H-NMR, (13)C-NMR, IR, MS, and elemental analysis. A preliminary in vitro bioassay indicated that compounds TMa, TMe and TMf displayed excellent fungicidal activity against Rhizoctonia solani and could be used as potential lead compounds for further development of novel fungicides. MDPI 2014-06-17 /pmc/articles/PMC6271209/ /pubmed/24941339 http://dx.doi.org/10.3390/molecules19068140 Text en © 2014 by the authors. licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Liu, Yuanyuan
Li, Yi
Chen, Nanqing
Lv, Kunzhi
Zhou, Chao
Xiong, Xiaohui
Li, Fangshi
Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety
title Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety
title_full Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety
title_fullStr Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety
title_full_unstemmed Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety
title_short Synthesis and Fungicidal Activity of Novel Chloro-Containing 1-Aryl-3-oxypyrazoles with an Oximino Ester or Oximino Amide Moiety
title_sort synthesis and fungicidal activity of novel chloro-containing 1-aryl-3-oxypyrazoles with an oximino ester or oximino amide moiety
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271209/
https://www.ncbi.nlm.nih.gov/pubmed/24941339
http://dx.doi.org/10.3390/molecules19068140
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