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Diastereoselective Three-Component Reactions of Chiral Nickel(II) Glycinate for Convenient Synthesis of Novel α-Amino-β-Substituted-γ,γ-Disubstituted Butyric Acids

The convenient, high yielding and diastereoselective synthesis of α-amino-β-substituted-γ,γ-disubstituted butyric acid derivatives was carried out by a three-component tandem reaction of a chiral equivalent of nucleophilic glycine. The reaction was performed smoothly under mild conditions and enable...

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Detalles Bibliográficos
Autores principales: Zhou, Rui, Guo, Li, Peng, Cheng, He, Gu, Ouyang, Liang, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271210/
https://www.ncbi.nlm.nih.gov/pubmed/24434695
http://dx.doi.org/10.3390/molecules19010826