Cargando…

Diastereoselective Three-Component Reactions of Chiral Nickel(II) Glycinate for Convenient Synthesis of Novel α-Amino-β-Substituted-γ,γ-Disubstituted Butyric Acids

The convenient, high yielding and diastereoselective synthesis of α-amino-β-substituted-γ,γ-disubstituted butyric acid derivatives was carried out by a three-component tandem reaction of a chiral equivalent of nucleophilic glycine. The reaction was performed smoothly under mild conditions and enable...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Rui, Guo, Li, Peng, Cheng, He, Gu, Ouyang, Liang, Huang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271210/ https://www.ncbi.nlm.nih.gov/pubmed/24434695 http://dx.doi.org/10.3390/molecules19010826

Ejemplares similares

Ambidexterity and Left-Handedness Induced by Geminally Disubstituted γ Amino Acid Residues in Chiral 3(10) Helices
por: Debnath, Swapna, et al.
Publicado: (2023)

Diastereoselective radical addition to γ-alkyl-α-methylene-γ-butyrolactams and the synthesis of a chiral pyroglutamic acid derivative
por: Yajima, Tomoko, et al.
Publicado: (2013)

Diastereoselective Synthesis of γ- and δ-Lactams from Imines and Sulfone-Substituted Anhydrides
por: Sorto, Nohemy A., et al.
Publicado: (2014)

Base-Promoted Synthesis of β-Substituted-Tryptophans via a Simple and Convenient Three-Component Condensation of Nickel(II) Glycinate
por: Zhou, Rui, et al.
Publicado: (2017)

Nickel-Catalyzed Amidoalkylation Reaction of γ-Hydroxy Lactams: An Access to 3-Substituted Isoindolinones†
por: Zhang, Shuo, et al.
Publicado: (2019)

Trityl Cation-Catalyzed Hosomi-Sakurai Reaction of Allylsilane with β,γ-Unsaturated α-Ketoester to Form γ,γ-Disubstituted α-Ketoesters
por: Gan, Zubao, et al.
Publicado: (2022)

Regio- and diastereoselective reactions of chiral secondary alkylcopper reagents with propargylic phosphates: preparation of chiral allenes
por: Skotnitzki, Juri, et al.
Publicado: (2020)

A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams
por: Aksenov, Alexander V., et al.
Publicado: (2023)

Long-range diastereoselectivity in Ugi reactions of 2-substituted dihydrobenzoxazepines
por: Banfi, Luca, et al.
Publicado: (2011)

A convenient synthesis of γ-functionalized cyclopentenones
por: Lahmar, Nour, et al.
Publicado: (2005)

Chiral‐at‐Iron Catalyst for Highly Enantioselective and Diastereoselective Hetero‐Diels‐Alder Reaction
por: Hong, Yubiao, et al.
Publicado: (2021)

Diastereoselective Ugi reaction of chiral 1,3-aminoalcohols derived from an organocatalytic Mannich reaction
por: Caputo, Samantha, et al.
Publicado: (2016)

Copper‐Catalyzed Enantio‐ and Diastereoselective Addition of Silicon Nucleophiles to 3,3‐Disubstituted Cyclopropenes
por: Zhang, Liangliang, et al.
Publicado: (2019)

Diastereoselective synthesis of chiral 1,3-cyclohexadienals
por: Urosa, Aitor, et al.
Publicado: (2018)

trans-Diastereoselective Syntheses of γ-Lactones by Visible Light-Iodine-Mediated Carboesterification of Alkenes
por: Maejima, Saki, et al.
Publicado: (2019)

Diastereoselective Amplification of a Mechanically Chiral [2]Catenane
por: Caprice, Kenji, et al.
Publicado: (2021)

Conformational transitions induced by γ-amino butyrate binding in GabR, a bacterial transcriptional regulator
por: Frezzini, Mario, et al.
Publicado: (2019)

An enzyme free simultaneous detection of γ-amino-butyric acid and testosterone based on copper oxide nanoparticles
por: Hussain, Mohammad Musarraf, et al.
Publicado: (2021)

Regioselectivity and diastereoselectivity of three-component reaction of α-amino acid, dialkyl acetylenedicarboxylates and 2-arylidene-1,3-indanediones
por: Chen, Liang, et al.
Publicado: (2017)

Diastereoselective Synthesis of cis-2,6-Disubstituted Dihydropyrane Derivatives through a Competitive Silyl-Prins Cyclization versus Alternative Reaction Pathways
por: Peña, Laura F., et al.
Publicado: (2023)

Multiple pathways for the formation of the γ-glutamyl peptides γ-glutamyl-valine and γ- glutamyl-valyl-glycine in Saccharomyces cerevisiae
por: Sofyanovich, Olga A., et al.
Publicado: (2019)

Synthesis of Polyoxygenated Heterocycles by Diastereoselective Functionalization of a Bio-Based Chiral Aldehyde Exploiting the Passerini Reaction
por: Vitali Forconesi, Gabriella, et al.
Publicado: (2020)

Directed nickel-catalyzed regio- and diastereoselective arylamination of unactivated alkenes
por: Xie, Leipeng, et al.
Publicado: (2021)

Facile access to chiral γ-butyrolactones via rhodium-catalysed asymmetric hydrogenation of γ-butenolides and γ-hydroxybutenolides
por: Zhou, Yuxuan, et al.
Publicado: (2023)

Synthesis of Chiral 1,4-Disubstituted-1,2,3-Triazole Derivatives from Amino Acids
por: Klein, Michael, et al.
Publicado: (2009)

Organocatalyzed ring-opening reactions of γ-carbonyl-substituted ε-caprolactones
por: Ota, Takayuki, et al.
Publicado: (2023)

Diastereoselective C–H carbonylative annulation of aliphatic amines: a rapid route to functionalized γ-lactams
por: Png, Zhuang Mao, et al.
Publicado: (2018)

Efficient, highly diastereoselective MS 4 Å-promoted one-pot, three-component synthesis of 2,6-disubstituted-4-tosyloxytetrahydropyrans via Prins cyclization
por: Ahmed, Naseem, et al.
Publicado: (2012)

Identification, Classification and Screening for γ-Amino-butyric Acid Production in Lactic Acid Bacteria from Cambodian Fermented Foods
por: Ly, Dalin, et al.
Publicado: (2019)

Memantine Improves the Disturbed Glutamine and γ-Amino Butyric Acid Homeostasis in the Brain of Rats Subjected to Experimental Autoimmune Encephalomyelitis
por: Dąbrowska-Bouta, Beata, et al.
Publicado: (2023)

Phytophenol Dimerization Reaction: From Basic Rules to Diastereoselectivity and Beyond
por: Liu, Shuqin, et al.
Publicado: (2022)

Synthesis of Substituted Oxo-Azepines by Regio- and Diastereoselective Hydroxylation
por: Spedding, Harold, et al.
Publicado: (2017)

Origin of the Diastereoselectivity of the Heterogeneous Hydrogenation of a Substituted Indolizine
por: Cormanich, Rodrigo A., et al.
Publicado: (2020)

Diastereoselective C-alkylation of aldimines, derived from chiral α-carbon heteroatom-substituted aldehydes, with triethylborane. Application to the synthesis of benzylisoquinolines
por: Fuentes-Ríos, David, et al.
Publicado: (2023)

Diastereoselectivity in the Staudinger reaction of pentafluorosulfanylaldimines and ketimines
por: Penger, Alexander, et al.
Publicado: (2013)

Regio- and Diastereoselective Carbometalation Reaction of Cyclopropenes
por: Cohen, Yair, et al.
Publicado: (2022)

Highly diastereoselective preparation of chiral NHC-boranes stereogenic at the boron atom
por: Aupic, Clara, et al.
Publicado: (2019)

Role of Cinchona Alkaloids in the Enantio- and Diastereoselective Synthesis of Axially Chiral Compounds
por: Portolani, Chiara, et al.
Publicado: (2022)

Dynamic kinetic resolution of γ,γ-disubstituted indole 2-carboxaldehydes via NHC-Lewis acid cooperative catalysis for the synthesis of tetracyclic ε-lactones
por: Balanna, Kuruva, et al.
Publicado: (2022)

Synthesis and Oxidative Transformations of New Chiral Pinane-Type γ-Ketothiols: Stereochemical Features of Reactions
por: Lezina, Olga M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5pvg7idqqfvf8olvlgvjmqh4sh