Anti-Proliferative and Apoptosis-Inducing Effects of Camptothecin-20(s)-O-(2-pyrazolyl-1)acetic Ester in Human Breast Tumor MCF-7 Cells

Camptothecin-20(s)-O-(2-pyrazolyl-1)acetic ester (CPT6) is a novel semi-synthetic analog of camptothecin. In a previous report, CPT6 possessed higher cytotoxic activity in vitro towards human breast tumor MCF-7 cells than topotecan. In this study, the antitumor activity of CPT6 on the human breast t...

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Detalles Bibliográficos
Autores principales: Chu, Chu, Xu, Jialin, Cheng, Dongping, Li, Xingnuo, Tong, Shengqiang, Yan, Jizong, Li, Qingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271214/
https://www.ncbi.nlm.nih.gov/pubmed/24747650
http://dx.doi.org/10.3390/molecules19044941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271214/
https://www.ncbi.nlm.nih.gov/pubmed/24747650
http://dx.doi.org/10.3390/molecules19044941

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