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Pharmacokinetics, Tissue Distribution and Excretion of Verticinone from F. hupehensis in Rats
Verticinone, the main active component in F. hupehensis, exhibits potent antitussive and expectorant effects. Here, a LC-MS method was developed and applied to study the pharmacokinetics, tissue distribution and excretion of verticinone in rats, and its plasma protein binding in vitro. A significant...
Autores principales: | Wu, Xiao, Sun, Jian-Guo, Peng, Ying, Liang, Yan, Wang, Guang-Ji, Chen, Hui, Wu, Ji-Zhou, Zhang, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271218/ https://www.ncbi.nlm.nih.gov/pubmed/25514053 http://dx.doi.org/10.3390/molecules191220613 |
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