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Diethyl 2-(Phenylcarbamoyl)phenyl Phosphorothioates: Synthesis, Antimycobacterial Activity and Cholinesterase Inhibition

A new series of 27 diethyl 2-(phenylcarbamoyl)phenyl phosphorothioates (thiophosphates) was synthesized, characterized by NMR, IR and CHN analyses and evaluated against Mycobacterium tuberculosis H(37)Rv, Mycobacterium avium and two strains of Mycobacterium kansasii. The best activity against M. tub...

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Detalles Bibliográficos
Autores principales: Vinšová, Jarmila, Krátký, Martin, Komlóová, Markéta, Dadapeer, Echchukattula, Štěpánková, Šárka, Vorčáková, Katarína, Stolaříková, Jiřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271228/
https://www.ncbi.nlm.nih.gov/pubmed/24886941
http://dx.doi.org/10.3390/molecules19067152