A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobi...

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Autores principales: Xia, Qing, Zhang, Huazheng, Sun, Xuefei, Zhao, Haijuan, Wu, Lingfang, Zhu, Dan, Yang, Guanghui, Shao, Yanyan, Zhang, Xiaoxue, Mao, Xin, Zhang, Lanzhen, She, Gaimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271249/
https://www.ncbi.nlm.nih.gov/pubmed/25361420
http://dx.doi.org/10.3390/molecules191117478
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author Xia, Qing
Zhang, Huazheng
Sun, Xuefei
Zhao, Haijuan
Wu, Lingfang
Zhu, Dan
Yang, Guanghui
Shao, Yanyan
Zhang, Xiaoxue
Mao, Xin
Zhang, Lanzhen
She, Gaimei
author_facet Xia, Qing
Zhang, Huazheng
Sun, Xuefei
Zhao, Haijuan
Wu, Lingfang
Zhu, Dan
Yang, Guanghui
Shao, Yanyan
Zhang, Xiaoxue
Mao, Xin
Zhang, Lanzhen
She, Gaimei
author_sort Xia, Qing
collection PubMed
description Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and (13)C-NMR spectral data.
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spelling pubmed-62712492019-01-07 A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp. Xia, Qing Zhang, Huazheng Sun, Xuefei Zhao, Haijuan Wu, Lingfang Zhu, Dan Yang, Guanghui Shao, Yanyan Zhang, Xiaoxue Mao, Xin Zhang, Lanzhen She, Gaimei Molecules Review Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and (13)C-NMR spectral data. MDPI 2014-10-30 /pmc/articles/PMC6271249/ /pubmed/25361420 http://dx.doi.org/10.3390/molecules191117478 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xia, Qing
Zhang, Huazheng
Sun, Xuefei
Zhao, Haijuan
Wu, Lingfang
Zhu, Dan
Yang, Guanghui
Shao, Yanyan
Zhang, Xiaoxue
Mao, Xin
Zhang, Lanzhen
She, Gaimei
A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
title A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
title_full A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
title_fullStr A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
title_full_unstemmed A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
title_short A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
title_sort comprehensive review of the structure elucidation and biological activity of triterpenoids from ganoderma spp.
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271249/
https://www.ncbi.nlm.nih.gov/pubmed/25361420
http://dx.doi.org/10.3390/molecules191117478
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