Design, Synthesis and SAR Study of Novel Trisubstituted Pyrimidine Amide Derivatives as CCR4 Antagonists

The design, synthesis and structure-activity relationship studies of some novel trisubstituted pyrimidine amide derivatives prepared as CCR4 antagonists are described. The activities of these compounds were evaluated by the CCR4-MDC chemotaxis inhibition assay. Compound 1, which we have previously r...

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Detalles Bibliográficos
Autores principales: Xu, Libao, Zhang, Yang, Dai, Wenjie, Wang, Ying, Jiang, Dan, Wang, Lili, Xiao, Junhai, Yang, Xiaohong, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271259/
https://www.ncbi.nlm.nih.gov/pubmed/24662072
http://dx.doi.org/10.3390/molecules19033539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271259/
https://www.ncbi.nlm.nih.gov/pubmed/24662072
http://dx.doi.org/10.3390/molecules19033539

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