ROS-Dependent Antiproliferative Effect of Brassinin Derivative Homobrassinin in Human Colorectal Cancer Caco2 Cells

This study was designed to examine the in vitro antiproliferative effect of brassinin and its derivatives on human cancer cell lines. Among seven tested compounds, homobrassinin (K1; N-[2-(indol-3-yl)ethyl]-S-methyldithiocarbamate) exhibited the most potent activity with IC(50) = 8.0 μM in human col...

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Detalles Bibliográficos
Autores principales: Kello, Martin, Drutovic, David, Chripkova, Martina, Pilatova, Martina, Budovska, Mariana, Kulikova, Lucia, Urdzik, Peter, Mojzis, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271261/
https://www.ncbi.nlm.nih.gov/pubmed/25068784
http://dx.doi.org/10.3390/molecules190810877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271261/
https://www.ncbi.nlm.nih.gov/pubmed/25068784
http://dx.doi.org/10.3390/molecules190810877

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