Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2

Five new 2(5H)-furanone-type derivatives, pestalafuranones F–J (compounds 3–7), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The stru...

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Detalles Bibliográficos
Autores principales: Zhang, Hongqi, Deng, Zhangshuang, Guo, Zhiyong, Tu, Xuan, Wang, Junzhi, Zou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271264/
https://www.ncbi.nlm.nih.gov/pubmed/24434694
http://dx.doi.org/10.3390/molecules19010819
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author Zhang, Hongqi
Deng, Zhangshuang
Guo, Zhiyong
Tu, Xuan
Wang, Junzhi
Zou, Kun
author_facet Zhang, Hongqi
Deng, Zhangshuang
Guo, Zhiyong
Tu, Xuan
Wang, Junzhi
Zou, Kun
author_sort Zhang, Hongqi
collection PubMed
description Five new 2(5H)-furanone-type derivatives, pestalafuranones F–J (compounds 3–7), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The structures of these metabolites were elucidated by EIMS, HREIMS and NMR spectroscopic data. Compounds 1–7 exhibited no cytotoxic activities against the MDA-MB-231 and Caski cancer cell lines.
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spelling pubmed-62712642018-12-20 Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2 Zhang, Hongqi Deng, Zhangshuang Guo, Zhiyong Tu, Xuan Wang, Junzhi Zou, Kun Molecules Article Five new 2(5H)-furanone-type derivatives, pestalafuranones F–J (compounds 3–7), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The structures of these metabolites were elucidated by EIMS, HREIMS and NMR spectroscopic data. Compounds 1–7 exhibited no cytotoxic activities against the MDA-MB-231 and Caski cancer cell lines. MDPI 2014-01-10 /pmc/articles/PMC6271264/ /pubmed/24434694 http://dx.doi.org/10.3390/molecules19010819 Text en © 2014 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zhang, Hongqi
Deng, Zhangshuang
Guo, Zhiyong
Tu, Xuan
Wang, Junzhi
Zou, Kun
Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2
title Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2
title_full Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2
title_fullStr Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2
title_full_unstemmed Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2
title_short Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2
title_sort pestalafuranones f–j, five new furanone analogues from the endophytic fungus nigrospora sp. bm-2
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271264/
https://www.ncbi.nlm.nih.gov/pubmed/24434694
http://dx.doi.org/10.3390/molecules19010819
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