Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions. The title compounds were evaluated for antileishmanial activity in vitro against Leishmania amazonensis...

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Detalles Bibliográficos
Autores principales: de Araújo, Morgana V., de Souza, Patricia S. O., de Queiroz, Aline C., da Matta, Carolina B. B., Leite, Anderson Brandão, da Silva, Amanda Evelyn, de França, José A. A., Silva, Tania M. S., Camara, Celso A., Alexandre-Moreira, Magna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271274/
https://www.ncbi.nlm.nih.gov/pubmed/25247686
http://dx.doi.org/10.3390/molecules190915180

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